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Bacteriostatic water also can't be used for IV administration without an isotonic admixture, because plain bacteriostatic water without a solute is hypotonic and can cause hemolysis on IV push

The compound's development represents years of medicinal chemistry optimization, resulting in a 10-fold improvement in potency over parent compounds while maintaining excellent safety margins in preclinical studies

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Studies using magnetic resonance imaging and liver biopsy have shown significant reductions in hepatic steatosis with GLP-1 receptor agonist therapy